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Protocols

The filing cabinet — every clinical protocol held in the library, with its current version, amendment history, and the study it belongs to.

Read-only catalog. Protocol versioning and amendments flow through the Essential Documents agent; promotion to live requires a Part 11 e-signature.

Total

12

Active

5

Draft

1

Amended

2

Closed

2

Total MB

31.1

Acme Therapeutics

4 protocols
  • Acemyebrelin 600 mg dose-expansion in r/r multiple myeloma

    PROT-ONC-002 · STUDY-2025-001 · Phase 2b

    Relapsed/refractory multiple myeloma

    Active
    Current version
    v3.0
    Last amended
    2mo ago
    Amendments
    3
    Size
    2.3 MB
    pdfdocxFiled by Dr. P. Adler (Medical Monitor)
  • Acemyebrelin protocol amendment 4 — CrCl entry criterion relaxation

    PROT-ONC-002-AMEND4 · STUDY-2025-001 · Phase 2b

    Relapsed/refractory multiple myeloma

    In review
    Current version
    v3.1-draft
    Last amended
    16d ago
    Amendments
    0
    Size
    1.9 MB
    docxFiled by A. Bahari (Regulatory Lead)
  • First-in-human Ph1 SAD/MAD of brivomelin in healthy volunteers

    PROT-NEU-021 · standalone · Phase 1

    Healthy volunteer pharmacology — neurology programme

    Draft
    Current version
    v0.4
    Last amended
    12d ago
    Amendments
    0
    Size
    988.4 KB
    docxFiled by Dr. P. Adler (Medical Monitor)
  • Open-label Ph1b combination with checkpoint inhibitor in advanced NSCLC

    PROT-ONC-004 · standalone · Phase 1

    Advanced non-small-cell lung cancer (2L+)

    In review
    Current version
    v1.0
    Last amended
    1mo ago
    Amendments
    0
    Size
    1.2 MB
    pdfdocxFiled by S. Iyer (Sponsor Regulatory)

Helios Cardio

2 protocols
  • Event-driven Ph3 CV outcomes study in post-MI elevated Lp(a)

    PROT-CV-118 · STUDY-2023-021 · Phase 3

    Reduction of MACE in post-MI patients with elevated Lp(a)

    Active
    Current version
    v5.2
    Last amended
    10mo ago
    Amendments
    5
    Size
    6.1 MB
    pdfdocxxmlFiled by J. Park (Sponsor Program Lead)
  • Ph4 post-approval safety study of lorivastatin in primary prevention

    PROT-CV-121 · standalone · Phase 4

    Primary cardiovascular prevention — statin-naive adults

    Active
    Current version
    v2.0
    Last amended
    8mo ago
    Amendments
    2
    Size
    2.0 MB
    pdfxmlFiled by J. Park (Sponsor Program Lead)

Lyra Skin Sciences

1 protocol
  • Combination device + topical Ph2a study in moderate-to-severe AD

    PROT-DERM-003 · STUDY-2024-014 · Phase 2a

    Moderate-to-severe atopic dermatitis (combination device)

    Active
    Current version
    v2.1
    Last amended
    6mo ago
    Amendments
    2
    Size
    1.6 MB
    pdfdocxFiled by Dr. N. Okafor (Sponsor PI)

Northwind Genetics

2 protocols
  • Pivotal Ph3 placebo-controlled study of velpoxetide in adult XLH

    PROT-RARE-007 · STUDY-2025-002 · Phase 3

    X-linked hypophosphatemia in adults

    Amended
    Current version
    v4.0
    Last amended
    3mo ago
    Amendments
    4
    Size
    4.2 MB
    pdfdocxxmlFiled by L. Romero (Sponsor Regulatory)
  • Natural history study of MPS-IIIb in paediatric subjects

    PROT-RARE-009 · standalone · Observational

    Mucopolysaccharidosis type IIIb (Sanfilippo-B) — paediatric

    Active
    Current version
    v1.2
    Last amended
    6mo ago
    Amendments
    1
    Size
    1.8 MB
    pdfdocxFiled by L. Romero (Sponsor Regulatory)

Stellis Vaccines

2 protocols
  • Adjuvanted RSV prefusion-F vaccine Ph2b dose-finding in older adults

    PROT-VAX-014 · STUDY-2025-008 · Phase 2b

    Respiratory syncytial virus in older adults

    Amended
    Current version
    v2.3
    Last amended
    4mo ago
    Amendments
    3
    Size
    2.9 MB
    pdfdocxFiled by M. Chen (CMC Lead)
  • Closed-out Ph2a pandemic-flu adjuvant comparison

    PROT-VAX-009 · standalone · Phase 2a

    Pandemic influenza adjuvant comparison

    Closed
    Current version
    v3.0-final
    Last amended
    1y ago
    Amendments
    3
    Size
    2.7 MB
    pdfdocxxmlFiled by M. Chen (CMC Lead)

Veridian Pharma

1 protocol
  • PASS 5-year safety registry of verexitide in T2DM

    PROT-OBS-PMR-001 · STUDY-2022-009 · Observational

    Long-term safety surveillance of verexitide in T2DM

    Closed
    Current version
    v1.4-final
    Last amended
    29d ago
    Amendments
    4
    Size
    3.4 MB
    pdfxmlFiled by K. Reyes (Records Lead)