Glossary

64 terms across 6 categories. Every acronym and concept used across the platform — ALCOA+, Part 11, autonomy classes, GAMP 5, CDISC, RAG, and more.

Anthropic Claude— Anthropic Claude model family
System
The LLM provider for this platform. Sonnet 4.7 is the default; Opus 4.7 is used for high-stakes reasoning. Model IDs are pinned in packages/model-registry/.
See also: Model registry, RAG
CTMS— Clinical Trial Management System
System
The system of record for study operations: sites, visits, milestones, monitoring activity. The platform integrates with CTMS through services/integrations/ctms/.
See also: eTMF, EDC
Drizzle— Drizzle ORM
System
The TypeScript ORM used across this monorepo. Schemas live in packages/schema/. drizzle-kit generates SQL migrations that are applied to Supabase.
See also: Supabase
eCOA— Electronic Clinical Outcome Assessment
System
Tablet/phone-based capture of patient-reported, clinician-reported, or observer-reported outcomes. Feeds EDC.
See also: EDC, RTSM
EDC— Electronic Data Capture
System
The system clinical sites use to enter subject-level data (eCRFs). The platform reads from and writes to EDC through services/integrations/edc/, never directly.
See also: eCOA, CTMS, SDV
eTMF— Electronic Trial Master File
System
The regulated document repository for a clinical trial — the inspector first stop. Indexed against the DIA TMF Reference Model. Agent 04 (Essential Documents) writes proposed eTMF entries to staging.
See also: CTMS, EDC
Inngest— Inngest (deferred)
System
Durable workflow / job runtime. Deferred for the demo era (per ADR 0006) in favor of Vercel Cron + Supabase pg_cron. Re-evaluate when durable multi-step workflows or fan-out retries become unavoidable.
See also: Vercel Cron
Model registry— packages/model-registry
System
Internal registry pinning every prompt + model version used by an agent. CI fails if a prompt diff lands without a corresponding registry row bump.
See also: Anthropic Claude
Neo4j— Neo4j (deferred)
System
Graph database originally planned for relationship-heavy agent reasoning. Deferred per ADR 0006 until an agent genuinely needs graph traversal.
See also: pgvector
OMS— Operations Management System
System
Internal CRO operations system covering resourcing, contracts, and finance. Distinct from CTMS (study ops) and eTMF (documents).
See also: CTMS, eTMF
pgvector— Postgres vector extension
System
The Postgres extension storing embedding vectors for similarity search. Enabled on the Supabase project; powers RAG retrieval without a separate vector database.
See also: RAG, Supabase
RAG— Retrieval-Augmented Generation
System
LLM pattern that retrieves relevant documents (via vector search) and grounds the model response in them. The platform knowledge-RAG agent uses pgvector for retrieval and citation grounding for trust.
See also: pgvector, Anthropic Claude
RTSM— Randomization and Trial Supply Management
System
System that randomizes subjects to treatment arms and manages drug supply / dispensation. Integrates with EDC for kit codes and unblinding workflows.
See also: EDC, CTMS
Supabase— Supabase (Postgres + Auth)
System
Managed Postgres + Auth + Realtime used as the platform data spine. Project ref clkifpedvomnpgajdsid, us-east-1, pgvector enabled, RLS deny-by-default.
See also: pgvector, Drizzle
Vercel Cron— Vercel Cron + Supabase pg_cron
System
Scheduled-job mechanism for the demo era (ADR 0006). Vercel Cron triggers HTTP endpoints; pg_cron handles in-database periodic work. Replaces the originally planned Inngest workflows.
See also: Inngest